Your life can move brain science forward. If you are fifty plus with limited life expectancy, you may qualify for one PET scan. Enrollment includes consent for after death brain donation. Families receive a free brain autopsy report and $2,000 funeral support after donation.
This study is testing an investigational PET brain scan that may help researchers better understand brain changes linked to Alzheimer’s disease and other illnesses. By comparing brain scans taken during life with findings after death, doctors hope to learn how to diagnose these conditions more accurately in the future.
This study is testing an investigational PET brain scan that may help researchers better understand brain changes linked to Alzheimer’s disease and other illnesses. By comparing brain scans taken during life with findings after death, doctors hope to learn how to diagnose these conditions more accurately in the future.
Adults age 50 and older who have a serious illness and who may have about one year or less to live. People both with and without Alzheimer’s or dementia may be eligible. A family member or legally authorized representative may also help with enrollment.
• A brief screening visit (health history, consent, and basic checks). Study staff can travel to you to help with consent and answer questions.
• One PET brain scan with an investigational tracer. Transportation support is available to help you get to and from the scan.
• A short safety follow-up phone call.
• An optional MRI or amyloid scan, if recommended and you are comfortable.
• Required consent for brain donation after death to compare scan results with brain tissue findings.
Yes. Donation of the brain after death is required to participate. This is always discussed respectfully, and families’ wishes, religious beliefs, and traditions are honored.
No. The report is focused on the brain only, to compare with the scan findings. It is a neuropathology brain report, not a full-body autopsy report.
The tracer used for the PET scan involves a small amount of radiation, similar to other medical imaging procedures. Possible side effects include mild headaches or dizziness. There is no promise of direct medical benefit from joining.
All study-related procedures are provided at no cost.
Yes. Families of participants who pass away while enrolled and complete brain donation receive $2,000 in funeral support plus a brain autopsy report.
The study is being conducted at research centers across the United States. When you apply, you’ll be matched with the location closest to you.
Yes. Participation is completely voluntary. You may choose to stop at any time, and your regular medical care will not be affected.
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