Help shape research of Parkinson’s disease care
Living with Parkinson's Disease?
A clinical trial is studying an investigational therapy for Stage 3–4 Parkinson’s disease.
Study-related care may be provided at no cost to eligible participants.
Travel support may be available.
See if you qualify
Fill out the form below to see if you could qualify for the study.
What's Involved?
If you pass the screening process and are deemed eligible, you will be randomized into the study to undergo a minimally invasive procedure or sham procedure, followed by a short hospital stay
You’ll have follow up visits over approximately two years
After the study you’ll check-in with your regular doctor annually for long-term observation
Frequently Asked Questions
What are the benefits of DSP-1083?
The benefit of the experimental therapy is unknown
Will there be a placebo?
Yes. Participants in the first Cohort (3-5 patients) will all get the investigational treatment. The next 20 participants will be split into 2 groups evenly, 10 receiving DSP-1083 during the surgical procedure and 10 having a surgical procedure only, with no cell administration. Participants will not know which group they are in. Subjects who receive DSP-1083 will receive immunosuppressant medications, while the group who have a surgical procedure only will receive placebos.
Who are the surgeons performing the surgeries?
The neurosurgeons selected for this study were qualified based on previous neurosurgical experience including deep brain stimulation, gene and/or cell therapies.
Will I have to pay for anything?
No. If you qualify and choose to participate, all study-related procedures, surgery, and medications are provided at no cost.
Why is participation so long?
Screening for this study is extensive and will last approximately 3 months. Once the surgery is performed, participants will be monitored and observed for approximately 2 years.
What if I no longer want to participate?
Participation is entirely voluntary. You can stop participating at any time for any reason.
What support is available?
Travel, hotel, and meal expenses are covered for you and one caregiver during study visits.
Is the treatment FDA-approved?
No, DSP-1083 is investigational and only available through this study.
Why are you asking about race or ethnicity?
This study is enrolling participants from a specific racial group at the beginning of the trial to ensure representation in early data. Researchers are committed to studying this therapy in a diverse population.
Please note: 1nHealth may store your data in a confidential and secure database. That personal information will never be shared or sold with any other persons or organizations not associated with 1nHealth. 1nHealth may/will use personal information to contact you directly by phone and/or email for matters related to potential participation in clinical trials, studies, and projects for which the potential participant may qualify. See our Privacy Policy for more details.